Key Messages

Given the recent surge in COVID-19 across Chicago and Illinois, clinicians should familiarize themselves with the clinical presentation, evaluation, management, and reporting requirements for Multisystem inflammatory syndrome in children (MIS-C).
MIS-C occurs within about 4 weeks of an acute SARS-CoV-2 infection. Increased cases of MIS-C have been seen 3-4 weeks following surges of acute COVID transmission.
A high index of suspicion should be maintained for MIS-C cases following the current wave of COVID caused by the Omicron variant.
COVID-19 vaccination is highly effective in preventing MIS-C.
Report MIS-C in Chicago residents to CDPH by following instructions on the HAN page and described below.
Attend the upcoming CDC COCA call on Thursday, February 10, 2022 at 1p-2p Central:
- COVID-19 Updates: What Clinicians Need to Know About Multisystem Inflammatory Syndrome in Children

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