Zika virus infection should be considered in patients with acute onset of fever, maculopapular rash, arthralgia or conjunctivitis, who traveled to areas with active transmission in the two weeks prior to illness onset.  The illness is usually mild with symptoms lasting from several days to a week. Severe disease requiring hospitalization is uncommon.  

Zika infection during pregnancy can cause a birth defect of the brain called microcephaly and other severe fetal brain defects. Other problems have been detected among fetuses and infants infected with Zika virus before birth, such as defects of the eye, hearing deficits, and impaired growth. There have also been increased reports of Guillain-Barré syndrome, an uncommon sickness of the nervous system, in areas affected by Zika.

Because of possible associations with poor pregnancy outcomes, the CDC recommends that pregnant women in any trimester and women trying to become pregnant consider postponing travel to areas with active Zika transmission.

There is no vaccine to prevent Zika. The best way to prevent diseases spread by mosquitoes is to protect yourself and your family from mosquito bites.